Sonochemical synthesis of molybdenum oxide (MoO3) microspheres anchored graphitic carbon nitride (g-C3N4) ultrathin sheets for enhanced electrochemical sensing of Furazolidone

•A novel molybdenum oxide microspheres was synthesized by a facile sonochemical method.•MoO3 were coupled with graphitic carbon nitride ultrathin sheets via ultrasonication.•The g-C3N4/MoO3/GCE can detect the FU with a limit of detection of 1.4 nM. Present strategy introduce the sonochemical synthesis of molybdenum oxide (MoO3) microspheres anchored graphitic carbon nitride (g-C3N4) ultrathin sheets as a novel electrocatalyst for the detection of Furazolidone (FU). TEM results revealed that MoO3 are microspheres with an average size of 2 µM and the g-C3N4 seems like ultrathin sheets. Owing to their peculiar morphological structure, g-C3N4/MoO3 composite modified electrode provided an enriched electroactive surface area (0.3788 cm2) and higher heterogeneous electron transfer kinetics (K°eff = 4.91×10−2 cm s−1) than the other controlled electrodes. It is obviously observed from the voltammetric studies that the proposed sensor based on g-C3N4/MoO3 composite can significantly improve the electrocatalytic efficiency towards the sensing of FU. Due to the excellent synergic effect of g-C3N4/MoO3 composite, can detect the ultra-level FU with a limit of detection of 1.4 nM and a broad dynamic range of 0.01–228 µM, which surpassed the many previously reported FU sensors. Hence, the proposed sensor was successfully applied to sensing the FU in human blood serum, urine and pharmaceutical samples, gained an agreeable recoveries.