Oesophageal preservation in locally advanced oesophageal cancer – Authors' reply

Oesophageal preservation in locally advanced oesophageal cancer – Authors' reply

Previously, we showed that in 63 (89%) of all 71 non-complete responders, residual tumour cells could be found in the mucosa or submucosa, and only occasionally solely in the deeper layers (six of the eight in regional lymph nodes).2 The use of bite-on-bite biopsy theoretically increases the chance...

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Veröffentlicht in:The lancet oncology 2018-09, Vol.19 (9), p.e431-e431
Hauptverfasser: Noordman, Bo Jan, van Lanschot, J Jan B
Format: Artikel
Sprache:eng
Schlagworte:
Accuracy
Biopsy
Cancer
Chemoradiotherapy
Esophagus
Lymphatic system
Preservation
Surveillance
Tumors
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Zusammenfassung:Previously, we showed that in 63 (89%) of all 71 non-complete responders, residual tumour cells could be found in the mucosa or submucosa, and only occasionally solely in the deeper layers (six of the eight in regional lymph nodes).2 The use of bite-on-bite biopsy theoretically increases the chance of detecting residual cancer cells in the submucosal layer of the oesophagus, compared with regular biopsy. [...]we believe that a small amount of residual disease (
ISSN:1470-2045
1474-5488
DOI:10.1016/S1470-2045(18)30619-3