Rhabdomyolysis and acute renal failure associated with the co-administration of daptomycin and an HMG-CoA reductase inhibitor

Rhabdomyolysis and acute renal failure associated with the co-administration of daptomycin and an HMG-CoA reductase inhibitor

The first case of creatine phosphokinase elevation with rhabdomyolysis and acute renal failure that developed during the co-administration of daptomycin and an HMG-CoA reductase inhibitor is discussed. Symptoms resolved after discontinuation of daptomycin.

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Veröffentlicht in:Journal of antimicrobial chemotherapy 2009-06, Vol.63 (6), p.1299-1300
Hauptverfasser: Odero, Randy O., Cleveland, Kerry O., Gelfand, Michael S.
Format: Artikel
Sprache:eng
Schlagworte:
Acute Kidney Injury - etiology
Anti-Bacterial Agents - adverse effects
Antibiotics
Bacteria
Chemotherapy
creatine phosphokinase
Daptomycin - adverse effects
Drug Therapy, Combination
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects
interstitial nephritis
Kidney diseases
linezolid
Rhabdomyolysis - chemically induced
Rhabdomyolysis - complications
Side effects
simvastatin
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Zusammenfassung:The first case of creatine phosphokinase elevation with rhabdomyolysis and acute renal failure that developed during the co-administration of daptomycin and an HMG-CoA reductase inhibitor is discussed. Symptoms resolved after discontinuation of daptomycin.
ISSN:0305-7453
1460-2091
DOI:10.1093/jac/dkp127