Design Effect of Metallic (Durable) and Polymeric (Resorbable) Stents on Blood Flow and Platelet Activation

Design Effect of Metallic (Durable) and Polymeric (Resorbable) Stents on Blood Flow and Platelet Activation

Bioresorbable vascular scaffolds (BVS) provide transient vessel support for occluded coronary arteries while resorbing over time, potentially allowing vessel restoration approximating the native, healthy state. Clinical trials indicate that the Absorb BVS (Abbott Vascular, Santa Clara, CA) performan...

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Veröffentlicht in:Artificial organs 2018-12, Vol.42 (12), p.1148-1156
Hauptverfasser: Marom, Gil, Eswaran, Senthil K., Rapoza, Richard J., Hossainy, Syed F. A., Slepian, Marvin J., Bluestein, Danny
Format: Artikel
Sprache:eng
Schlagworte:
Activation
Arteries
Biocompatibility
Biomedical materials
Bioresorbable scaffolds
Blood flow
Blood platelets
Blood vessels
Clinical trials
Complications
Computational fluid dynamics
Computer applications
Coronary artery
Coronary stents
Design
Fluid dynamics
Hemodynamics
Hydrodynamics
Implants
Medical research
Platelets
Probability distribution
Restoration
Stenosis
Stents
Struts
Surgical implants
Thickness
Thromboembolism
Thrombogenicity
Thrombosis
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Zusammenfassung:Bioresorbable vascular scaffolds (BVS) provide transient vessel support for occluded coronary arteries while resorbing over time, potentially allowing vessel restoration approximating the native, healthy state. Clinical trials indicate that the Absorb BVS (Abbott Vascular, Santa Clara, CA) performance was similar to that of the Xience metallic drug‐eluting stent (DES), with low long‐term complications rates. However, when under‐deployed in very small vessels (diameter
ISSN:0160-564X
1525-1594
DOI:10.1111/aor.13276