Multicenter study on parathyroidectomy (PTX) in Italy: preliminary results

Background When medical therapy is unable to achieve biochemical control of secondary hyperparathyroidism, parathyroidectomy (PTX) is indicated, fortunately in a minority of patients. Thus, data on PTX prevalence and biochemical control are limited and, in particular in Italy, date back to 1999. Met...

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Veröffentlicht in:Journal of nephrology 2018-10, Vol.31 (5), p.767-773
Hauptverfasser: Mazzaferro, Sandro, Tartaglione, Lida, Cascone, Carmelo, Di Daniele, Nicola, Pani, Antonello, Morosetti, Massimo, Francisco, Marco, Nordio, Maurizio, Leonardi, Maria, Martello, Mauro, Grimaldi, Cristina, Cozzolino, Mario, Rotondi, Silverio, Pasquali, Marzia
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Sprache:eng
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Zusammenfassung:Background When medical therapy is unable to achieve biochemical control of secondary hyperparathyroidism, parathyroidectomy (PTX) is indicated, fortunately in a minority of patients. Thus, data on PTX prevalence and biochemical control are limited and, in particular in Italy, date back to 1999. Methods We designed a prospective, observational and multicenter study to collect data from dialysis units distributed throughout the Italian regions. Clinical data were collected with a dedicated data sheet. Results From January to December 2010, 149 Centers serving a total of 12,515 patients provided data on 528 living PTX cases (PTX prevalence = 4.2%). Prevalence was higher in hemo- than in peritoneal dialysis (4.5 vs. 1.9%, X 2  = 21.52; p 
ISSN:1121-8428
1724-6059
DOI:10.1007/s40620-018-0527-x