Insights into Proteasome Conformation Dynamics and Intersubunit Communication
A recently published paper applies cryo-electron microscopy (EM) studies and biochemical/genetic approaches for the elucidation of the mechanisms linking nucleotide binding by ATPases, proteasome conformation dynamics, and gate opening of the 20S core particle. These insights potentially represent a...
Gespeichert in:
| Veröffentlicht in: | Trends in biochemical sciences (Amsterdam. Regular ed.) 2018-11, Vol.43 (11), p.852-853 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 853 |
|---|---|
| container_issue | 11 |
| container_start_page | 852 |
| container_title | Trends in biochemical sciences (Amsterdam. Regular ed.) |
| container_volume | 43 |
| creator | Tundo, Grazia R. Sbardella, Diego Coletta, Massimo |
| description | A recently published paper applies cryo-electron microscopy (EM) studies and biochemical/genetic approaches for the elucidation of the mechanisms linking nucleotide binding by ATPases, proteasome conformation dynamics, and gate opening of the 20S core particle. These insights potentially represent a milestone in our understanding of the structural dynamics of the 26S proteasome. |
| doi_str_mv | 10.1016/j.tibs.2018.08.002 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2094410530</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0968000418301506</els_id><sourcerecordid>2094410530</sourcerecordid><originalsourceid>FETCH-LOGICAL-c356t-ec880d6cc56d5c386c26ecc311348a559cf825ea59ea3b7dc03cbba6896167543</originalsourceid><addsrcrecordid>eNp9kE1P4zAQhq0VCArLH-CAcuSSMrZjJ5G4oPJViRV72D1bzmS6uGpssJ2V-PekFDgijTRzeN5XmoexUw5zDlxfrOfZdWkugDdzmAbEDzbjUouykkLvsRm0uikBoDpkRymtAbiqa3XADiXwSgGvZ-zX0if37ymnwvkcit8xZLIpDFQsgl-FONjsgi-uX70dHKbC-r5Y-kwxjd3oXZ6wYZgOfOd-sv2V3SQ6-djH7O_tzZ_FffnweLdcXD2UKJXOJWHTQK8Rle4Vykaj0IQoOZdVY5VqcdUIRVa1ZGVX9wgSu87qptVc16qSx-x81_scw8tIKZvBJaTNxnoKYzIC2qrioCRMqNihGENKkVbmObrBxlfDwWw1mrXZajRbjQamATGFzj76x26g_ivy6W0CLncATV_-dxRNQkceqXeRMJs-uO_63wAFNoSf</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2094410530</pqid></control><display><type>article</type><title>Insights into Proteasome Conformation Dynamics and Intersubunit Communication</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Tundo, Grazia R. ; Sbardella, Diego ; Coletta, Massimo</creator><creatorcontrib>Tundo, Grazia R. ; Sbardella, Diego ; Coletta, Massimo</creatorcontrib><description>A recently published paper applies cryo-electron microscopy (EM) studies and biochemical/genetic approaches for the elucidation of the mechanisms linking nucleotide binding by ATPases, proteasome conformation dynamics, and gate opening of the 20S core particle. These insights potentially represent a milestone in our understanding of the structural dynamics of the 26S proteasome.</description><identifier>ISSN: 0968-0004</identifier><identifier>EISSN: 1362-4326</identifier><identifier>DOI: 10.1016/j.tibs.2018.08.002</identifier><identifier>PMID: 30145017</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adenosine Triphosphatases ; allosteric interactions ; ATPase cycle ; conformation dynamics ; core particles-regulatory particles interaction ; Cryoelectron Microscopy ; Molecular Conformation ; proteasome assembly ; Proteasome Endopeptidase Complex</subject><ispartof>Trends in biochemical sciences (Amsterdam. Regular ed.), 2018-11, Vol.43 (11), p.852-853</ispartof><rights>2018 Elsevier Ltd</rights><rights>Copyright © 2018 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-ec880d6cc56d5c386c26ecc311348a559cf825ea59ea3b7dc03cbba6896167543</citedby><cites>FETCH-LOGICAL-c356t-ec880d6cc56d5c386c26ecc311348a559cf825ea59ea3b7dc03cbba6896167543</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0968000418301506$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30145017$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tundo, Grazia R.</creatorcontrib><creatorcontrib>Sbardella, Diego</creatorcontrib><creatorcontrib>Coletta, Massimo</creatorcontrib><title>Insights into Proteasome Conformation Dynamics and Intersubunit Communication</title><title>Trends in biochemical sciences (Amsterdam. Regular ed.)</title><addtitle>Trends Biochem Sci</addtitle><description>A recently published paper applies cryo-electron microscopy (EM) studies and biochemical/genetic approaches for the elucidation of the mechanisms linking nucleotide binding by ATPases, proteasome conformation dynamics, and gate opening of the 20S core particle. These insights potentially represent a milestone in our understanding of the structural dynamics of the 26S proteasome.</description><subject>Adenosine Triphosphatases</subject><subject>allosteric interactions</subject><subject>ATPase cycle</subject><subject>conformation dynamics</subject><subject>core particles-regulatory particles interaction</subject><subject>Cryoelectron Microscopy</subject><subject>Molecular Conformation</subject><subject>proteasome assembly</subject><subject>Proteasome Endopeptidase Complex</subject><issn>0968-0004</issn><issn>1362-4326</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1P4zAQhq0VCArLH-CAcuSSMrZjJ5G4oPJViRV72D1bzmS6uGpssJ2V-PekFDgijTRzeN5XmoexUw5zDlxfrOfZdWkugDdzmAbEDzbjUouykkLvsRm0uikBoDpkRymtAbiqa3XADiXwSgGvZ-zX0if37ymnwvkcit8xZLIpDFQsgl-FONjsgi-uX70dHKbC-r5Y-kwxjd3oXZ6wYZgOfOd-sv2V3SQ6-djH7O_tzZ_FffnweLdcXD2UKJXOJWHTQK8Rle4Vykaj0IQoOZdVY5VqcdUIRVa1ZGVX9wgSu87qptVc16qSx-x81_scw8tIKZvBJaTNxnoKYzIC2qrioCRMqNihGENKkVbmObrBxlfDwWw1mrXZajRbjQamATGFzj76x26g_ivy6W0CLncATV_-dxRNQkceqXeRMJs-uO_63wAFNoSf</recordid><startdate>201811</startdate><enddate>201811</enddate><creator>Tundo, Grazia R.</creator><creator>Sbardella, Diego</creator><creator>Coletta, Massimo</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201811</creationdate><title>Insights into Proteasome Conformation Dynamics and Intersubunit Communication</title><author>Tundo, Grazia R. ; Sbardella, Diego ; Coletta, Massimo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-ec880d6cc56d5c386c26ecc311348a559cf825ea59ea3b7dc03cbba6896167543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adenosine Triphosphatases</topic><topic>allosteric interactions</topic><topic>ATPase cycle</topic><topic>conformation dynamics</topic><topic>core particles-regulatory particles interaction</topic><topic>Cryoelectron Microscopy</topic><topic>Molecular Conformation</topic><topic>proteasome assembly</topic><topic>Proteasome Endopeptidase Complex</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tundo, Grazia R.</creatorcontrib><creatorcontrib>Sbardella, Diego</creatorcontrib><creatorcontrib>Coletta, Massimo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Trends in biochemical sciences (Amsterdam. Regular ed.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tundo, Grazia R.</au><au>Sbardella, Diego</au><au>Coletta, Massimo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Insights into Proteasome Conformation Dynamics and Intersubunit Communication</atitle><jtitle>Trends in biochemical sciences (Amsterdam. Regular ed.)</jtitle><addtitle>Trends Biochem Sci</addtitle><date>2018-11</date><risdate>2018</risdate><volume>43</volume><issue>11</issue><spage>852</spage><epage>853</epage><pages>852-853</pages><issn>0968-0004</issn><eissn>1362-4326</eissn><abstract>A recently published paper applies cryo-electron microscopy (EM) studies and biochemical/genetic approaches for the elucidation of the mechanisms linking nucleotide binding by ATPases, proteasome conformation dynamics, and gate opening of the 20S core particle. These insights potentially represent a milestone in our understanding of the structural dynamics of the 26S proteasome.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>30145017</pmid><doi>10.1016/j.tibs.2018.08.002</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0968-0004 |
| ispartof | Trends in biochemical sciences (Amsterdam. Regular ed.), 2018-11, Vol.43 (11), p.852-853 |
| issn | 0968-0004 1362-4326 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2094410530 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adenosine Triphosphatases allosteric interactions ATPase cycle conformation dynamics core particles-regulatory particles interaction Cryoelectron Microscopy Molecular Conformation proteasome assembly Proteasome Endopeptidase Complex |
| title | Insights into Proteasome Conformation Dynamics and Intersubunit Communication |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T02%3A08%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Insights%20into%20Proteasome%20Conformation%20Dynamics%20and%20Intersubunit%20Communication&rft.jtitle=Trends%20in%20biochemical%20sciences%20(Amsterdam.%20Regular%20ed.)&rft.au=Tundo,%20Grazia%20R.&rft.date=2018-11&rft.volume=43&rft.issue=11&rft.spage=852&rft.epage=853&rft.pages=852-853&rft.issn=0968-0004&rft.eissn=1362-4326&rft_id=info:doi/10.1016/j.tibs.2018.08.002&rft_dat=%3Cproquest_cross%3E2094410530%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2094410530&rft_id=info:pmid/30145017&rft_els_id=S0968000418301506&rfr_iscdi=true |