Nanoparticle Delivery of miRNA-21 Mimic to Cardiac Macrophages Improves Myocardial Remodeling after Myocardial Infarction

MicroRNA-based therapy that targets cardiac macrophages holds great potential for treatment of myocardial infarction (MI). Here, we explored whether boosting the miRNA-21 transcript level in macrophage-enriched areas of the infarcted heart could switch their phenotype from pro-inflammatory to repara...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nano letters 2018-09, Vol.18 (9), p.5885-5891
Hauptverfasser:	Bejerano, Tzlil, Etzion, Sharon, Elyagon, Sigal, Etzion, Yoram, Cohen, Smadar
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!