Insects Go on a STING Operation to Tackle Intracellular Invaders

Insect immunity to extracellular microbes relies largely on the TOLL and IMD pathways. In this issue of Immunity, Goto et al. (2018) report that the IKKβ-Relish module of the IMD pathway hitches up the intracellular sensor STING to activate antiviral responses in Drosophila. Insect immunity to extra...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2018-08, Vol.49 (2), p.195-197
Hauptverfasser:	Zakovic, Suzana, Levashina, Elena A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Deoxyribonucleic acid DNA Endoplasmic reticulum Fruit flies Immunity Infections Insect immunity Insects Intracellular Listeria Sting operations Studies Tropical diseases Viral infections Viruses
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Beschreibung
Zusammenfassung:	Insect immunity to extracellular microbes relies largely on the TOLL and IMD pathways. In this issue of Immunity, Goto et al. (2018) report that the IKKβ-Relish module of the IMD pathway hitches up the intracellular sensor STING to activate antiviral responses in Drosophila. Insect immunity to extracellular microbes relies largely on the TOLL and IMD pathways. In this issue of Immunity, Goto et al. (2018) report that the IIKKβ-Relish module of the IMD pathway hitches up the intracellular sensor STING to activate antiviral responses in Drosophila.
ISSN:	1074-7613 1097-4180
DOI:	10.1016/j.immuni.2018.08.003