Low serum butyrylcholinesterase is independently related to low fetuin-A in patients on hemodialysis: a cross-sectional study

Low serum butyrylcholinesterase is independently related to low fetuin-A in patients on hemodialysis: a cross-sectional study

Purpose Fetuin-A, which plays a protective role against the atherosclerosis and progression of vascular calcification, is decreased in patients on hemodialysis (HD). Fetuin-A and serum butyrylcholinesterase (BChE) levels decrease during malnutrition. We explored whether BChE was independently relate...

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Veröffentlicht in:International urology and nephrology 2018-09, Vol.50 (9), p.1713-1720
Hauptverfasser: Okamoto, Teppei, Tsutaya, Chikako, Hatakeyama, Shingo, Konishi, Sakae, Okita, Kazutaka, Tanaka, Yoshimi, Imanishi, Kengo, Takashima, Tooru, Saitoh, Fumitada, Suzuki, Tadashi, Ohyama, Chikara
Format: Artikel
Sprache:eng
Schlagworte:
Aged
alpha-2-HS-Glycoprotein - metabolism
Aorta
Aorta, Abdominal - diagnostic imaging
Arteriosclerosis
Butyrylcholinesterase - blood
C-reactive protein
C-Reactive Protein - metabolism
Calcification
Calcification (ectopic)
Cardiovascular diseases
Computed tomography
Cross-Sectional Studies
Female
Hemodialysis
Humans
Kidney Failure, Chronic - blood
Laboratories
Male
Malnutrition
Medicine
Medicine & Public Health
Middle Aged
Multivariate analysis
Nephrology
Nephrology - Original Paper
Nutritional Status
Renal Dialysis
ROC Curve
Serum Albumin - metabolism
Urology
Vascular Calcification - drug therapy
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Zusammenfassung:Purpose Fetuin-A, which plays a protective role against the atherosclerosis and progression of vascular calcification, is decreased in patients on hemodialysis (HD). Fetuin-A and serum butyrylcholinesterase (BChE) levels decrease during malnutrition. We explored whether BChE was independently related to fetuin-A in patients on HD. Methods Laboratory data including BChE and serum fetuin-A were acquired from 230 patients on HD between August 2017 and April 2018. Nutritional status was evaluated using the Geriatric Nutritional Risk Index (GNRI). Abdominal aortic calcification index (ACI) was measured using computed tomography. Patients were stratified into two groups: low fetuin-A (
ISSN:0301-1623
1573-2584
DOI:10.1007/s11255-018-1957-z