Research status and progress of biomaterials for bone repair and reconstruction

Artificial bone repair material is the best substitute for autologous bone transplantation. Bone repair materials are constantly being replaced and upgraded, which can be roughly divided into three generations: bioinert materials, bioactive materials, and smart materials. Research and development of bone repair materials with multiple biological activities, degradation property that perfectly fit for new bone formation, and ability of complete reconstruction of bone tissue in physiological state are the focus of future research.