Lymph node transplantation for the treatment of lymphedema

Lymph node transplantation for the treatment of lymphedema

Lymphedema is a complex disease process with deranged lymphatic transport, fluid accumulation and secondary lipedema and fibrosis. This is a challenging disease to treat with a surgical focus on debulking and physiologic strategies. One strategy is the use of vascularized lymph node transplant (VLNT...

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Veröffentlicht in:Journal of surgical oncology 2018-10, Vol.118 (5), p.736-742
Hauptverfasser: Gould, Daniel J, Mehrara, Babak J, Neligan, Peter, Cheng, Ming‐Huei, Patel, Ketan M
Format: Artikel
Sprache:eng
Schlagworte:
Anastomosis, Surgical
Cancer surgery
Free Tissue Flaps
Humans
Lipectomy
Lymph Nodes - blood supply
Lymph Nodes - transplantation
Lymphangiogenesis
lymphatic surgery
Lymphatic system
Lymphedema
Lymphedema - surgery
Surgical techniques
Transplant Donor Site
Transplantation, Heterotopic
Transplants & implants
vascularized lymph node transplant (VLNT)
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Beschreibung
Zusammenfassung:Lymphedema is a complex disease process with deranged lymphatic transport, fluid accumulation and secondary lipedema and fibrosis. This is a challenging disease to treat with a surgical focus on debulking and physiologic strategies. One strategy is the use of vascularized lymph node transplant (VLNT) to improve physiologic lymph clearance. In this article, VLNT is discussed in detail, including mechanisms, combined strategies, and outcomes.
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.25180