C‐reactive protein/albumin ratio is a poor prognostic factor of esophagogastric junction and upper gastric cancer

Background and Aim The C‐reactive protein (CRP)/albumin (Alb) ratio has been reported as a novel prognostic marker in several cancers. The objective of this study was to investigate the prognostic value of the CRP/Alb ratio in patients who underwent surgery for adenocarcinoma of the esophagogastric...

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Veröffentlicht in:Journal of gastroenterology and hepatology 2019-02, Vol.34 (2), p.355-363
Hauptverfasser: Kudou, Kensuke, Saeki, Hiroshi, Nakashima, Yuichiro, Kamori, Tomohiro, Kawazoe, Tetsuro, Haruta, Yasuhiro, Fujimoto, Yoshiaki, Matsuoka, Hiroya, Sasaki, Shun, Jogo, Tomoko, Hirose, Kosuke, Hu, Qingjiang, Tsuda, Yasuo, Kimura, Koichi, Ando, Koji, Oki, Eiji, Ikeda, Tetsuo, Maehara, Yoshihiko
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Sprache:eng
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Zusammenfassung:Background and Aim The C‐reactive protein (CRP)/albumin (Alb) ratio has been reported as a novel prognostic marker in several cancers. The objective of this study was to investigate the prognostic value of the CRP/Alb ratio in patients who underwent surgery for adenocarcinoma of the esophagogastric junction (AEG) and upper gastric cancer (UGC). Methods Data for 144 patients who underwent surgery for AEG and UGC were reviewed. The CRP/Alb ratio, neutrophil–lymphocyte ratio, platelet–lymphocyte ratio, Glasgow Prognostic Score, and controlling nutritional status score were calculated, and the relationship between these biomarkers and postoperative prognosis was analyzed. Results The optimal cutoff value of the CRP/Alb ratio was determined to be 0.1. According to the cutoff value of CRP/Alb ratio, patients were divided into two groups (CRP/Alb 
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.14442