A pH-responsive nanoprobe for turn-on 19F-magnetic resonance imaging

A pH-responsive nanoprobe for turn-on 19F-magnetic resonance imaging

We successfully fabricated 19F magnetic resonance imaging (MRI) nanoprobes by partly replacing the 2-methylimidazolate of the metal organic framework (MOF) matrix ZIF-8, of which the strong 19F MRI signal displays an interesting pH dependence property, indicating its great potential as a 19F MRI con...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2018-01, Vol.54 (70), p.9853-9856
Hauptverfasser: Guo, Chang, Xu, Suying, Arshad, Anila, Wang, Leyu
Format: Artikel
Sprache:eng ; jpn
Schlagworte:
Contrast agents
Dependence
Magnetic resonance imaging
Metal-organic frameworks
NMR
Nuclear magnetic resonance
Penetration depth
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Zusammenfassung:We successfully fabricated 19F magnetic resonance imaging (MRI) nanoprobes by partly replacing the 2-methylimidazolate of the metal organic framework (MOF) matrix ZIF-8, of which the strong 19F MRI signal displays an interesting pH dependence property, indicating its great potential as a 19F MRI contrast agent for stimuli-responsive imaging with high penetration depth and low background.
ISSN:1359-7345
1364-548X
DOI:10.1039/c8cc06129g