Depression and psychological distress in patients with chronic renal failure: Prevalence and associated factors in a rural district in Sri Lanka

Chronic Kidney Disease (CKD) is known to adversely affect mental health. The study was aimed at estimating the prevalence of depression and psychological distress and the associated factors among CKD patients living in Anuradhapura, a rural district in Sri Lanka. A community-based, cross-sectional study included a representative sample of 1174 CKD patients, drawn proportionately from all registered patients in all 19 Medical Officer of Health areas in the district of Anuradhapura. Trained paramedical staff visited the households and administered the locally validated Centre for Epidemiologic Studies Depression Scale and General Health Questionnaire–12 to screen for depression and psychological distress. Information related to associated factors was obtained through an interviewer-administered questionnaire. A total of 1118 CKD patients participated, with a response rate of 95.2%. The mean age was 58.3 (SD 10.8) years. 62.7% of participants were males. The majority of participants was in CKD stage 4 (58.3%). The screening revealed that 75.0% (95% CI 72.5–77.5) of participants were psychologically distressed while 65.2% (95%CI 62.4–68.0) were found to be depressed. Multiple logistic regression analysis revealed advanced age, unemployment and poor health related quality of life contributed significantly to both depression and psychological distress. Depression and psychological distress were significant in this community. Policymakers should consider the likely high prevalence of psychological distress and depression among CKD patients as well as the need for specific mental health services to confirm diagnosis and initiate effective management. Identified associated factors should be used to identify targeted preventative interventions. •The prevalence of depression and psychological distress among Chronic Kidney Disease patients was found to be high.•Advanced age, unemployment and poor HRQOL are significantly associated with both depression and psychological distress.•Decision makers should advocate on the high prevalence of psychological distress and depression among CKD patients.•Identified factors associated should be used to identify targeted preventative interventions.