Effects of resistance plus aerobic training on body composition and metabolic markers in older breast cancer survivors undergoing aromatase inhibitor therapy

To evaluate the effects of combined aerobic + resistance training on body composition and metabolic markers in older breast cancer survivors undergoing aromatase inhibitor therapy. Older breast cancer survivors were randomized to an exercise [resistance + aerobic training]: n = 18, or placebo control group: n = 18. Body composition (measured by DXA) and blood markers of lipid and glucose were measured at baseline, and at 12, 24, and 36 weeks. The exercise group performed 40 min of resistance exercises on machines followed by 30 min of aerobic training on a treadmill, three times per week. Separate 2 (group) × 4 (time) repeated-measure ANOVAs were used to compare groups over time. Significant group × time interactions were found for total and trunk fat mass (p