Liver resection versus transarterial chemoembolization for the initial treatment of Barcelona Clinic Liver Cancer stage B hepatocellular carcinoma

Aims Current evidence supporting the efficacy of transarterial chemoembolization (TACE) in Barcelona Clinic Liver Cancer (BCLC)-B hepatocellular carcinoma (HCC) is controversial. The aim of this systematic review was to compare the benefits of liver resection (LR) versus TACE in BCLC-B HCC. Methods...

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Veröffentlicht in:Hepatology international 2018-09, Vol.12 (5), p.417-428
Hauptverfasser: Yang, Biao, Zheng, Bo, Yang, MaoNan, Zeng, Zhu, Yang, FangYun, Pu, Ji, Li, ChunLin, Liao, ZhengYin
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Sprache:eng
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Zusammenfassung:Aims Current evidence supporting the efficacy of transarterial chemoembolization (TACE) in Barcelona Clinic Liver Cancer (BCLC)-B hepatocellular carcinoma (HCC) is controversial. The aim of this systematic review was to compare the benefits of liver resection (LR) versus TACE in BCLC-B HCC. Methods We conducted a comprehensive literature review of the EMBASE, PubMed, Google Scholar, and Chinese Biomedical Literature databases for retrospective or prospective studies evaluating the efficacy of LR and TACE for the treatment of BCLC-B HCC. Results Eleven studies incorporating 3366 patients were included in this analysis. 1-year (RR 0.52 95% CI 0.43–0.63, p  
ISSN:1936-0533
1936-0541
DOI:10.1007/s12072-018-9888-4