Direct In Vivo Microbial Transcriptomics During Infection

Direct In Vivo Microbial Transcriptomics During Infection

The challenge in infectious diseases is monitoring infection in the host. Omics-based genomics and transcriptomics can define microbial genes expressed during infection and treatment with antimicrobials. Recent studies pinpoint a direct in situ in vivo approach revolutionizing infection monitoring a...

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Veröffentlicht in:Trends in microbiology (Regular ed.) 2018-09, Vol.26 (9), p.732-735
Hauptverfasser: Hébert, François-Olivier, Boyle, Brian, Levesque, Roger C.
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents
Antimicrobial agents
Drug resistance
Genomics
Humans
in vitro comparisons
In vivo methods and tests
in vivo transcription
Infections
Infectious diseases
Learning algorithms
Machine learning
microbial infections
Microorganisms
Monitoring
Pathogens
Pseudomonas aeruginosa
Pseudomonas Infections
Transcriptome
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Beschreibung
Zusammenfassung:The challenge in infectious diseases is monitoring infection in the host. Omics-based genomics and transcriptomics can define microbial genes expressed during infection and treatment with antimicrobials. Recent studies pinpoint a direct in situ in vivo approach revolutionizing infection monitoring and optimizing antimicrobial therapy using machine learning.
ISSN:0966-842X
1878-4380
DOI:10.1016/j.tim.2018.07.002