Hepatitis C Treatment for People With Severe Mental Illness

Over 4 million people in the United States are chronically infected with hepatitis C virus (HCV), and, if untreated, over 20% of these will progress to more serious disease. Persons with severe mental illness (SMI) have markedly elevated rates of HCV infection, but treatment of persons with SMI and...

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Veröffentlicht in:Psychosomatics (Washington, D.C.) D.C.), 2006-03, Vol.47 (2), p.93-107
Hauptverfasser: Mistler, Lisa A., Brunette, Mary F., Marsh, Bryan J., Vidaver, Robert M., Luckoor, Ravi, Rosenberg, Stanley D.
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container_end_page 107
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container_title Psychosomatics (Washington, D.C.)
container_volume 47
creator Mistler, Lisa A.
Brunette, Mary F.
Marsh, Bryan J.
Vidaver, Robert M.
Luckoor, Ravi
Rosenberg, Stanley D.
description Over 4 million people in the United States are chronically infected with hepatitis C virus (HCV), and, if untreated, over 20% of these will progress to more serious disease. Persons with severe mental illness (SMI) have markedly elevated rates of HCV infection, but treatment of persons with SMI and HCV has been controversial. Effective antiviral treatment is available, but side effects include depression and other neuropsychiatric symptoms. This article reviews the available data on neuropsychiatric side effects of interferon (IFN) treatment, discusses the limitations of the current research, and makes recommendations regarding HCV treatment in persons with SMI
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subjects Antiviral Agents - adverse effects
Biological and medical sciences
Depressive Disorder, Major - chemically induced
Depressive Disorder, Major - epidemiology
Hepatitis C virus
Hepatitis C, Chronic - drug therapy
Hepatitis C, Chronic - epidemiology
Human viral diseases
Humans
Infectious diseases
Interferons - adverse effects
Medical sciences
Mental Disorders - epidemiology
Viral diseases
Viral hepatitis
title Hepatitis C Treatment for People With Severe Mental Illness
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