Can short courses of systemic corticosteroids truly cause osteonecrosis?

Can short courses of systemic corticosteroids truly cause osteonecrosis?

ABSTRACT One of the most feared complications of long‐term corticosteroid therapy is osteonecrosis (avascular necrosis, aseptic necrosis). There is, no doubt, a causal role for systemic corticosteroids inducing osteonecrosis with such chronic therapy. The controversy involves whether short‐term (...

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Veröffentlicht in:Dermatologic therapy 2009-09, Vol.22 (5), p.458-464
1. Verfasser: Wolverton, Stephen E.
Format: Artikel
Sprache:eng
Schlagworte:
avascular necrosis
corticosteroids
Glucocorticoids - adverse effects
Glucocorticoids - therapeutic use
Humans
Kidney Transplantation - methods
Lupus Erythematosus, Systemic - drug therapy
osteonecrosis
Osteonecrosis - chemically induced
Osteonecrosis - physiopathology
prednisone
Risk Factors
Time Factors
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Zusammenfassung:ABSTRACT One of the most feared complications of long‐term corticosteroid therapy is osteonecrosis (avascular necrosis, aseptic necrosis). There is, no doubt, a causal role for systemic corticosteroids inducing osteonecrosis with such chronic therapy. The controversy involves whether short‐term (
ISSN:1396-0296
1529-8019
DOI:10.1111/j.1529-8019.2009.01262.x