Safety and Efficacy of Ledipasvir–Sofosbuvir With or Without Ribavirin for Chronic Hepatitis C in Children Ages 6‐11

Safety and Efficacy of Ledipasvir–Sofosbuvir With or Without Ribavirin for Chronic Hepatitis C in Children Ages 6‐11

Currently, there are no interferon‐free treatments available for hepatitis C virus (HCV)–infected patients younger than 12 years. We evaluated the safety and effectiveness of the all‐oral regimen ledipasvir–sofosbuvir ± ribavirin in HCV‐infected children aged 6 to

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Veröffentlicht in:Hepatology (Baltimore, Md.) Md.), 2018-12, Vol.68 (6), p.2158-2166
Hauptverfasser: Murray, Karen F., Balistreri, William F., Bansal, Sanjay, Whitworth, Suzanne, Evans, Helen M., Gonzalez‐Peralta, Regino P., Wen, Jessica, Massetto, Benedetta, Kersey, Kathryn, Shao, Jiang, Garrison, Kimberly L., Parhy, Bandita, Brainard, Diana M., Arnon, Ronen, Gillis, Lynette A., Jonas, Maureen M., Lin, Chuan‐Hao, Narkewicz, Michael R., Schwarz, Kathleen, Rosenthal, Philip
Format: Artikel
Sprache:eng
Schlagworte:
Antiviral drugs
Children
Cirrhosis
Fever
Fibrosis
Gastroenteritis
Genotype & phenotype
Genotypes
Headache
Hepatitis
Hepatitis C
Hepatology
Interferon
Liver cirrhosis
Pain
Patients
Ribavirin
Tablets
Teeth
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Zusammenfassung:Currently, there are no interferon‐free treatments available for hepatitis C virus (HCV)–infected patients younger than 12 years. We evaluated the safety and effectiveness of the all‐oral regimen ledipasvir–sofosbuvir ± ribavirin in HCV‐infected children aged 6 to
ISSN:0270-9139
1527-3350
DOI:10.1002/hep.30123