A photocaged fluorescent probe for imaging hypochlorous acid in lysosomes

A photocaged fluorescent probe for imaging hypochlorous acid in lysosomes

By combining the advantages of the photocaging technology and traditional analyte-responsive fluorescent probes, we designed and synthesized the first photocaged lysosomal-targeted fluorescent HOCl probe (PL-HA). The new caged PL-HA probe was capable of remote light-controlled recognition of HOCl in...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2018, Vol.54 (66), p.9238-9241
Hauptverfasser: Ren, Mingguang, Li, Zihong, Nie, Jing, Wang, Li, Lin, Weiying
Format: Artikel
Sprache:eng
Schlagworte:
Fluorescent indicators
Lysosomes
Technology assessment
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Beschreibung
Zusammenfassung:By combining the advantages of the photocaging technology and traditional analyte-responsive fluorescent probes, we designed and synthesized the first photocaged lysosomal-targeted fluorescent HOCl probe (PL-HA). The new caged PL-HA probe was capable of remote light-controlled recognition of HOCl in lysosomes.
ISSN:1359-7345
1364-548X
DOI:10.1039/c8cc04926b