Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan

Long-term exposure to inorganic arsenic from drinking water has been documented to induce cancers and vascular diseases in a dose-response relationship. A series of molecular environmental epidemiological studies have been carried out to elucidate biomarkers of exposure, effect, and susceptibility f...

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Veröffentlicht in:	Toxicology and applied pharmacology 2005-08, Vol.206 (2), p.198-206
Hauptverfasser:	Chen, Chien-Jen, Hsu, Lin-I, Wang, Chih-Hao, Shih, Wei-Liang, Hsu, Yi-Hsiang, Tseng, Mei-Ping, Lin, Yu-Chun, Chou, Wei-Ling, Chen, Chia-Yen, Lee, Cheng-Yeh, Wang, Li-Hua, Cheng, Yu-Chin, Chen, Chi-Ling, Chen, Shu-Yuan, Wang, Yuan-Hung, Hsueh, Yu-Mei, Chiou, Hung-Yi, Wu, Meei-Maan
Format:	Artikel
Sprache:	eng
Schlagworte:	Arsenic Arsenic - analysis Arsenic - toxicity Biomarkers Carcinoma, Transitional Cell - genetics Carotenoids - blood Chromosome Aberrations Environmental Monitoring Genes, p53 Genomic Instability Hair - chemistry Hazardous Substances - toxicity Health hazards Humans Loss of Heterozygosity Mutation Nails - chemistry Oxidative Stress Taiwan
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Zusammenfassung:	Long-term exposure to inorganic arsenic from drinking water has been documented to induce cancers and vascular diseases in a dose-response relationship. A series of molecular environmental epidemiological studies have been carried out to elucidate biomarkers of exposure, effect, and susceptibility for arsenic-related health hazards in Taiwan. Arsenic levels in urine, hair, and nail are biomarkers for short-term (
ISSN:	0041-008X 1096-0333
DOI:	10.1016/j.taap.2004.10.023