Hendrik Peter Bernelot Moens (1931-2008)

The synaptonemal complex (SC) is a proteinaceous structure that physically holds the two homologous chromosomes together during meiotic prophase. First observed in 1956 by Montrose J. Moses (Duke University, Durham, North Carolina) in meiotic prophase spermatocytes of crayfish, the SC was found in m...

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Veröffentlicht in:Genome 2008-12, Vol.51 (12), p.1063-1067
1. Verfasser: Marcon, Edyta
Format: Artikel
Sprache:eng
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Zusammenfassung:The synaptonemal complex (SC) is a proteinaceous structure that physically holds the two homologous chromosomes together during meiotic prophase. First observed in 1956 by Montrose J. Moses (Duke University, Durham, North Carolina) in meiotic prophase spermatocytes of crayfish, the SC was found in many other species. Initially, the research into the SC focused on its structural characteristics, but with the availability of antibodies, the focus shifted to the protein components of the complex, and later, attention was diverted to the proteins associated with this structure at different time points during meiotic prophase. Various possible roles of this meiotic-specific structure have been debated since the discovery of the SC structure but consensus has yet to be reached. Dr. Peter Moens has been an internationally recognized expert on the SC, being involved in all of the steps and characterizing many of the structural and functional components of the complex mainly in mice but also in other species.
ISSN:0831-2796
1480-3321
DOI:10.1139/G08-075