Cardiac myosin-binding protein C: how a novel biomarker could transform chest pain triage

[...]triage has become reliant on detection of elevated levels of the biomarker cardiac troponin (cTn) in the blood. [...]cMyC is a cardiac-restricted protein which rapidly enters the systemic circulation after myocardial injury and is relatively more abundant than troponin. Financial and competing interests disclosure The authors are supported by grants from the Medical Research Council (UK; G1000737), Guy's and St Thomas’ Charity (R060701, R100404), British Heart Foundation (TG/15/1/31518, FS/15/13/31320) and the UK Department of Health through the NIH Research Biomedical Research Centre award to Guy's and St Thomas’ NHS Foundation Trust.M Marber is named as an inventor on a patent held by King's College London for the detection of cMyC as a biomarker of myocardial injury. [...]universal definition of myocardial infarction.