A Novel Receptor-based Surface-plasmon-resonance Affinity Biosensor for Highly Sensitive and Selective Detection of Dopamine
We have established a new surface-plasmon-resonance (SPR) based affinity biosensor for highly sensitive and selective detection of dopamine (DA) employing a D3 dopamine receptor (D-RC) and a home-made DA-bovine serum albumin (DA-BSA) conjugate. The proposed biosensor is simple, reproducible and exhi...
Gespeichert in:
| Veröffentlicht in: | Chemistry letters 2006-06, Vol.35 (6), p.678-679 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | We have established a new surface-plasmon-resonance (SPR) based affinity biosensor for highly sensitive and selective detection of dopamine (DA) employing a D3 dopamine receptor (D-RC) and a home-made DA-bovine serum albumin (DA-BSA) conjugate. The proposed biosensor is simple, reproducible and exhibit excellent sensitivity for DA (detection limit = 85 pg/mL (ppt)) without any significant interference from ascorbic acid (AA), uric acid (UA), and other DA analogues. |
|---|---|
| ISSN: | 0366-7022 1348-0715 |
| DOI: | 10.1246/cl.2006.678 |