Chemopreventive effect of sulindac in combination with epigallocatechin gallate or kaempferol against 1,2‐dimethyl hydrazine‐induced preneoplastic lesions in rats: A Comparative Study

A systematic investigation of the chemopreventive effect of sulindac (SL) in combination with either epigallocatechin gallate (EGCG) or kaempferol similar (KMP) has been carried out 1,2‐dimethyl hydrazine‐treated rats (DMH). Those SL combinations with KMP and EGCG have enhanced the SL activity produ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of biochemical and molecular toxicology 2018-10, Vol.32 (10), p.e22198-N/A
Hauptverfasser:	Hassanein, Nahed M. A., Hassan, Eman S. G., Hegab, Amany M., Elahl, Helmy M. Sayd
Format:	Artikel
Sprache:	eng
Schlagworte:	1,2-Dimethylhydrazine - toxicity Animals Anticarcinogenic Agents - administration & dosage Anticarcinogenic Agents - pharmacology Antioxidants Apoptosis beta Catenin - blood beta Catenin - metabolism Carcinogens - toxicity Catechin - administration & dosage Catechin - analogs & derivatives Catechin - pharmacology Chemopreventive agents Colon Colon cancer Colonic Neoplasms - chemically induced Colonic Neoplasms - metabolism Colonic Neoplasms - prevention & control Colorectal cancer Comparative studies Cyclooxygenase 2 - metabolism dimethyl hydrazine Dimethylhydrazines Down-Regulation - drug effects Drug Therapy, Combination Epigallocatechin gallate Hydrazine Inflammation Kaempferol Kaempferols - administration & dosage Kaempferols - pharmacology Lesions Male Nitric oxide Nitric Oxide - metabolism Precancerous Conditions - chemically induced Precancerous Conditions - metabolism Precancerous Conditions - prevention & control Proliferating cell nuclear antigen Proliferating Cell Nuclear Antigen - metabolism Prostaglandin endoperoxide synthase Rats Rats, Sprague-Dawley Sulindac Sulindac - administration & dosage Sulindac - pharmacology Thiobarbituric Acid Reactive Substances - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!