Comparative UV-spectra of fermented cultural extract of antifungal-active Streptomyces isolates recovered from different ecological habitats

UV-spectra of antifungal-active Streptomyces isolates were compared to previously reported spectra and analyzed under different extraction conditions. MU123 Streptomyces isolate from Turkey exhibited a UV spectrum similar to 23 sub(7) isolate from Jordan with 2 maximum absorbance peaks at (226 and 260 nm) and at (220 and 260 nm), respectively. This spectrum was repeated by the C5P1 -6 isolate from Jordan with 2 maximum absorbance peaks at 225-250 and 300 nm. The aquatic species identified as S. violaceusniger showed 2 maximum absorbance peaks at 231 and 258 nm similar to the UV spectrum of a clinical isolate of actinomycetes (Streptomyces sp. 96.0333) that exhibited 2 absorbance peaks at 220-225 and 262 nm. When C1P2-6 isolate from Jordan was compared to Ir 102 from Iran under same cultural, extraction and UV analysis conditions, data revealed similar UV spectra with 2 absorbance peaks for both isolates at 200-225 and 275-300 nm. Approximately 50% of reported active screened isolates exhibit similar UV-spectra which might reflect their habitats, culture and UV analysis conditions. Comparison of UV-spectra and absorption peaks of known antibiotics to that of active Streptomyces isolates might explain the ability of the same Streptomyces sp. to produce several antibiotics.