Regiodivergent Copper Catalyzed Borocyanation of 1,3‐Dienes

Copper catalyzed multi‐functionalization of unsaturated carbon‐carbon bonds is a powerful tool for the generation of complex molecules. We report a regiodivergent process that allows a switch between 1,4‐borocupration and 4,1‐borocupration of 1,3‐dienes upon a simple change in ligand. The subsequently generated allyl coppers are trapped in an electrophilic cyanation to selectively generate densely functionalized and synthetically versatile 1,2‐ or 4,3‐borocyanation products. A powerful tool for the generation of complex molecules is the copper catalyzed multi‐functionalization of unsaturated carbon‐carbon bonds. A regiodivergent process that allows a switch between 1,4‐ and 4,1‐borocupration of 1,3‐dienes upon a simple change in ligand is described.