Microbiome metabolomics reveals new drivers of human liver steatosis

An integrative multiomics approach in nondiabetic obese women identifies phenylacetate as a microbial metabolite contributing to the accumulation of lipids in the liver and hence to nonalcoholic steatohepatitis.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature medicine 2018-07, Vol.24 (7), p.906-907
Hauptverfasser:	Delzenne, Nathalie M., Bindels, Laure B.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/326/2565/2134 631/443/319/320 692/699/1503/1607/2750 Amino acids Biomedical and Life Sciences Biomedicine Cancer Research Carcinoma Dehydrogenases Development and progression Fatty liver Feces Gene expression Genetic aspects Health aspects Hepatocellular carcinoma Infectious Diseases Lipid metabolism Lipids Liver Liver diseases Metabolic Diseases Metabolism Metabolites Metabolomics Microbiomes Microbiota Microbiota (Symbiotic organisms) Microorganisms Molecular Medicine Motor vehicle drivers Neurosciences News & Views news-and-views Nutrition Nutrition research Obesity Overweight persons Plasma Steatosis
Online-Zugang:	Volltext
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