Mild-to-Moderate Symptoms during the First Year of Antiretroviral Therapy Worsen Quality of Life in HIV-Infected Individuals

Symptoms and quality of life were assessed among human immunodeficiency virus (HIV)-infected individuals initiating their first course of antiretroviral therapy. Symptoms, which were mostly mild or moderate, were common in the first year and significantly affected the patients' quality of life....

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Veröffentlicht in:	Clinical infectious diseases 2008-03, Vol.46 (6), p.941-945
Hauptverfasser:	Mannheimer, Sharon B., Wold, Nicholas, Gardner, Edward M., Telzak, Edward E., Hullsiek, Katherine Huppler, Chesney, Margaret, Wu, Albert W., MacArthur, Rodger D., Matts, John, Friedland, Gerald
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS Anti-HIV Agents - adverse effects Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral drugs Antiretrovirals Antiviral agents Biological and medical sciences Clinical research Clinical trials Drug therapy Drug Therapy, Combination Female Highly active antiretroviral therapy HIV HIV infections HIV Infections - drug therapy HIV Infections - physiopathology HIV Infections - virology HIV Protease Inhibitors - adverse effects HIV Protease Inhibitors - therapeutic use HIV-1 - drug effects HIV/AIDS Human immunodeficiency virus Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Male Medical sciences Middle Aged Pharmacology. Drug treatments Quality of Life Reverse Transcriptase Inhibitors - adverse effects Reverse Transcriptase Inhibitors - therapeutic use Severity of Illness Index Symptoms Treatment Outcome Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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Beschreibung
Zusammenfassung:	Symptoms and quality of life were assessed among human immunodeficiency virus (HIV)-infected individuals initiating their first course of antiretroviral therapy. Symptoms, which were mostly mild or moderate, were common in the first year and significantly affected the patients' quality of life. Quality of life was inversely related to the number of symptoms and in the change in the number of symptoms from baseline.
ISSN:	1058-4838 1537-6591
DOI:	10.1086/528859