A new strategy for hydrophobic drug delivery using a hydrophilic polymer equipped with stacking units

A highly hydrophilic polymer equipped with guanidinium groups was used to load aromatic ring-containing hydrophobic agent doxorubicin (DOX) via π-π interaction. The results have shown that the delivery system exhibited enhanced cellular uptake and antitumor efficiency compared with free drugs. This...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2018, Vol.54 (59), p.8218-8221
Hauptverfasser:	Cui, Peng-Fei, Zhuang, Wan-Ru, Hu, Xi, Xing, Lei, Yu, Ru-Yi, Qiao, Jian-Bin, He, Yu-Jing, Li, Fangyuan, Ling, Daishun, Jiang, Hu-Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Doxorubicin Drug delivery systems Polymers
Online-Zugang:	Volltext
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