Systemic fluoride poisoning and death from inhalational exposure to sulfuryl fluoride

We report a poisoning death from inhalational exposure to the gas fumigants chloropicrin and sulfuryl fluoride. The patient displayed both local irritant effects of chloropicrin and systemic effects of sulfuryl fluoride. The clinical course, marked by initial hypocalcemia, delayed onset of ventricul...

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Veröffentlicht in:	Clinical toxicology (Philadelphia, Pa.) Pa.), 2008-11, Vol.46 (9), p.850-854
Hauptverfasser:	Schneir, Aaron, Clark, Richard F., Kene, Mamta, Betten, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Arrhythmias, Cardiac - chemically induced Biological and medical sciences Environmental Exposure - adverse effects Fatal Outcome Female Fluoride Poisoning - etiology Fumigation Humans Hydrocarbons, Chlorinated - poisoning Hypocalcemia - chemically induced Inhalation Exposure Insecticides - poisoning Medical sciences Sulfinic Acids - poisoning Toxicology
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Zusammenfassung:	We report a poisoning death from inhalational exposure to the gas fumigants chloropicrin and sulfuryl fluoride. The patient displayed both local irritant effects of chloropicrin and systemic effects of sulfuryl fluoride. The clinical course, marked by initial hypocalcemia, delayed onset of ventricular dysrhythmias, and death, is consistent with fluoride being the predominant mechanism of toxicity with sulfuryl fluoride.
ISSN:	1556-3650 1556-9519
DOI:	10.1080/15563650801938662