Pathogenesis of Infectious Disease of Mice Caused by H5N1 Avian Influenza Virus

The pathogenesis of a disease caused by Qinghai-like H5N1 influenza virus in BALB/c mice was studied. Clinical, morphological, and immunological characteristics of the experimental infection caused by highly pathogenic A/duck/Tuva/01/06/ (H5N1) virus are described.

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2008-12, Vol.146 (6), p.766-769
Hauptverfasser:	Evseenko, V. A., Sharshov, K. A., Bukin, E. K., Zaykovskaya, A. V., Ternovoy, V. A., Ignatyev, G. M., Shestopalov, A. M., Netesov, S. V., Shkurupiy, V. A., Drozdov, I. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Avian influenza virus Base Sequence Biomedical and Life Sciences Biomedicine Cell Biology Hemagglutinins - genetics Influenza A Virus, H5N1 Subtype - genetics Influenza A Virus, H5N1 Subtype - metabolism Influenza A Virus, H5N1 Subtype - pathogenicity Influenza virus Interferon-gamma - metabolism Interleukin-10 - metabolism Interleukin-12 - metabolism Interleukin-1beta - metabolism Interleukin-6 - metabolism Internal Medicine Laboratory Medicine Mice Mice, Inbred BALB C Neuraminidase - genetics Orthomyxoviridae Infections - pathology Orthomyxoviridae Infections - virology Pathology RNA Replicase - genetics Tumor Necrosis Factor-alpha - metabolism Viral Matrix Proteins - chemistry Viral Proteins - genetics Virology
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Beschreibung
Zusammenfassung:	The pathogenesis of a disease caused by Qinghai-like H5N1 influenza virus in BALB/c mice was studied. Clinical, morphological, and immunological characteristics of the experimental infection caused by highly pathogenic A/duck/Tuva/01/06/ (H5N1) virus are described.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-009-0375-8