Maximum likelihood estimation of the frequency of null alleles at microsatellite loci

Maximum likelihood estimation of the frequency of null alleles at microsatellite loci

We review three methods for estimating the frequency of null alleles at codominant loci (such as microsatellite loci) and present a new maximum likelihood approach. Computer simulations show that the maximum likelihood estimator has a smaller root mean squared error than previous estimators.

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Veröffentlicht in:Conservation genetics 2006-12, Vol.7 (6), p.991-995
Hauptverfasser: Kalinowski, Steven T, Taper, Mark L
Format: Artikel
Sprache:eng
Schlagworte:
computer simulation
Economic models
loci
microsatellite repeats
null alleles
Studies
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Beschreibung
Zusammenfassung:We review three methods for estimating the frequency of null alleles at codominant loci (such as microsatellite loci) and present a new maximum likelihood approach. Computer simulations show that the maximum likelihood estimator has a smaller root mean squared error than previous estimators.
ISSN:1566-0621
1572-9737
DOI:10.1007/s10592-006-9134-9