Evaluation of risk factors for oral infection with potential for spread in a 1-year cohort study
Objectives To determine the frequency of oral infection with potential for spread (OIPS) and behavioural risk factors in patients referred to a regional tertiary care-centre for OIPS assessment and clearance. Materials and methods A database search of all referrals to the Oral and Maxillofacial Dise...
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| Veröffentlicht in: | Clinical oral investigations 2019-02, Vol.23 (2), p.905-911 |
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| creator | Färkkilä, Esa Rautemaa-Richardson, Riina Färkkilä, Anniina Grönholm, Lotta Lauhio, Anneli |
| description | Objectives
To determine the frequency of oral infection with potential for spread (OIPS) and behavioural risk factors in patients referred to a regional tertiary care-centre for OIPS assessment and clearance.
Materials and methods
A database search of all referrals to the Oral and Maxillofacial Diseases unit of HUH in 2009 was performed. Of the 2807 referrals, 408 were due to a known or suspected OIPS. The electronic patient records of these patients were analysed for patient demographics, lifestyle factors, radiological findings and clinical oral findings. Risk factors for OIPS were analysed using logistic regression and using the significant factors in univariate analyses in the multivariate models.
Results
The mean age of the patients was 58 years. Most patients (
n
= 270, 66%) were referred due to upcoming cancer or other immunosuppressive therapy. The majority (
n
= 314, 77%) were diagnosed with one or more OIPS. In univariate analyses, smoking (OR 3.2, 95% CI 1.6–6.4;
p
= 0.0006), male gender (OR 1.7, 95% CI 1.1–2.8;
p
= 0.02), excessive alcohol use (OR 3.0, 95% 1.1–7.9;
p
= 0.03) and irregular dental care (OR 4.8, 95% CI 2.6–8.8;
p
|
| doi_str_mv | 10.1007/s00784-018-2518-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2060866636</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2060866636</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-eb8d13d4c4e655b01d932f93b6fa518053c6c6c1c909b24360f4d4db31e1b0883</originalsourceid><addsrcrecordid>eNp1kMtOAyEUhonR2Fp9ADeGxI2bUS4zDLM0Tb0kTdzoGhkGLHU6VGA0fXtpx0tiYkgOJHznh_MBcIrRJUaovAqp8DxDmGekSKXcA2OcU5bRssT7uzPJWMXxCByFsEQI56ykh2BEqirnhKMxeJ69y7aX0boOOgO9Da_QSBWdD9A4D52XLbSd0WqHfNi4gGsXdRdtutgSYe21bBIDJcTZRksPlVs4H2GIfbM5BgdGtkGffO0T8HQze5zeZfOH2_vp9TxTtCQx0zVvMG1ylWtWFDXCTUWJqWjNjEyjoYIqlhZWFapqkmZEJm_ypqZY4xpxTifgYshde_fW6xDFygal21Z22vVBEMQQZ4xRltDzP-jS9b5Lv0tUUVDGeUkShQdKeReC10asvV1JvxEYia1-MegXSb_Y6hdl6jn7Su7rlW5-Or59J4AMQLJmuxftf5_-P_UTmGWPJw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2055368872</pqid></control><display><type>article</type><title>Evaluation of risk factors for oral infection with potential for spread in a 1-year cohort study</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Färkkilä, Esa ; Rautemaa-Richardson, Riina ; Färkkilä, Anniina ; Grönholm, Lotta ; Lauhio, Anneli</creator><creatorcontrib>Färkkilä, Esa ; Rautemaa-Richardson, Riina ; Färkkilä, Anniina ; Grönholm, Lotta ; Lauhio, Anneli</creatorcontrib><description>Objectives
To determine the frequency of oral infection with potential for spread (OIPS) and behavioural risk factors in patients referred to a regional tertiary care-centre for OIPS assessment and clearance.
Materials and methods
A database search of all referrals to the Oral and Maxillofacial Diseases unit of HUH in 2009 was performed. Of the 2807 referrals, 408 were due to a known or suspected OIPS. The electronic patient records of these patients were analysed for patient demographics, lifestyle factors, radiological findings and clinical oral findings. Risk factors for OIPS were analysed using logistic regression and using the significant factors in univariate analyses in the multivariate models.
Results
The mean age of the patients was 58 years. Most patients (
n
= 270, 66%) were referred due to upcoming cancer or other immunosuppressive therapy. The majority (
n
= 314, 77%) were diagnosed with one or more OIPS. In univariate analyses, smoking (OR 3.2, 95% CI 1.6–6.4;
p
= 0.0006), male gender (OR 1.7, 95% CI 1.1–2.8;
p
= 0.02), excessive alcohol use (OR 3.0, 95% 1.1–7.9;
p
= 0.03) and irregular dental care (OR 4.8, 95% CI 2.6–8.8;
p
< 0.0001) were risk factors for OIPS. However, in multivariate analyses, smoking was the only independent risk factor for OIPS (OR 3.6, 95% CI 1.2–11.8;
p
= 0.02).
Conclusions
OIPS are common in patients referred for OIPS clearance, and smoking was identified as an independent behavioural risk factor for them. These findings highlight the burden of disease in this patient group and the importance of smoking cessation encouragement.
Clinical relevance
To identify patients at increased risk of OIPS.</description><identifier>ISSN: 1432-6981</identifier><identifier>EISSN: 1436-3771</identifier><identifier>DOI: 10.1007/s00784-018-2518-7</identifier><identifier>PMID: 29948280</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Cancer ; Cohort analysis ; Cohort Studies ; Demography ; Dentistry ; Drug addiction ; Female ; Finland ; Humans ; Immunosuppressive agents ; Infections - complications ; Infections - etiology ; Male ; Maxillofacial ; Medicine ; Middle Aged ; Oral infection ; Original Article ; Patients ; Risk Factors ; Stomatognathic Diseases - complications ; Stomatognathic Diseases - etiology</subject><ispartof>Clinical oral investigations, 2019-02, Vol.23 (2), p.905-911</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2018</rights><rights>Clinical Oral Investigations is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-eb8d13d4c4e655b01d932f93b6fa518053c6c6c1c909b24360f4d4db31e1b0883</citedby><cites>FETCH-LOGICAL-c372t-eb8d13d4c4e655b01d932f93b6fa518053c6c6c1c909b24360f4d4db31e1b0883</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00784-018-2518-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00784-018-2518-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29948280$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Färkkilä, Esa</creatorcontrib><creatorcontrib>Rautemaa-Richardson, Riina</creatorcontrib><creatorcontrib>Färkkilä, Anniina</creatorcontrib><creatorcontrib>Grönholm, Lotta</creatorcontrib><creatorcontrib>Lauhio, Anneli</creatorcontrib><title>Evaluation of risk factors for oral infection with potential for spread in a 1-year cohort study</title><title>Clinical oral investigations</title><addtitle>Clin Oral Invest</addtitle><addtitle>Clin Oral Investig</addtitle><description>Objectives
To determine the frequency of oral infection with potential for spread (OIPS) and behavioural risk factors in patients referred to a regional tertiary care-centre for OIPS assessment and clearance.
Materials and methods
A database search of all referrals to the Oral and Maxillofacial Diseases unit of HUH in 2009 was performed. Of the 2807 referrals, 408 were due to a known or suspected OIPS. The electronic patient records of these patients were analysed for patient demographics, lifestyle factors, radiological findings and clinical oral findings. Risk factors for OIPS were analysed using logistic regression and using the significant factors in univariate analyses in the multivariate models.
Results
The mean age of the patients was 58 years. Most patients (
n
= 270, 66%) were referred due to upcoming cancer or other immunosuppressive therapy. The majority (
n
= 314, 77%) were diagnosed with one or more OIPS. In univariate analyses, smoking (OR 3.2, 95% CI 1.6–6.4;
p
= 0.0006), male gender (OR 1.7, 95% CI 1.1–2.8;
p
= 0.02), excessive alcohol use (OR 3.0, 95% 1.1–7.9;
p
= 0.03) and irregular dental care (OR 4.8, 95% CI 2.6–8.8;
p
< 0.0001) were risk factors for OIPS. However, in multivariate analyses, smoking was the only independent risk factor for OIPS (OR 3.6, 95% CI 1.2–11.8;
p
= 0.02).
Conclusions
OIPS are common in patients referred for OIPS clearance, and smoking was identified as an independent behavioural risk factor for them. These findings highlight the burden of disease in this patient group and the importance of smoking cessation encouragement.
Clinical relevance
To identify patients at increased risk of OIPS.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cancer</subject><subject>Cohort analysis</subject><subject>Cohort Studies</subject><subject>Demography</subject><subject>Dentistry</subject><subject>Drug addiction</subject><subject>Female</subject><subject>Finland</subject><subject>Humans</subject><subject>Immunosuppressive agents</subject><subject>Infections - complications</subject><subject>Infections - etiology</subject><subject>Male</subject><subject>Maxillofacial</subject><subject>Medicine</subject><subject>Middle Aged</subject><subject>Oral infection</subject><subject>Original Article</subject><subject>Patients</subject><subject>Risk Factors</subject><subject>Stomatognathic Diseases - complications</subject><subject>Stomatognathic Diseases - etiology</subject><issn>1432-6981</issn><issn>1436-3771</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kMtOAyEUhonR2Fp9ADeGxI2bUS4zDLM0Tb0kTdzoGhkGLHU6VGA0fXtpx0tiYkgOJHznh_MBcIrRJUaovAqp8DxDmGekSKXcA2OcU5bRssT7uzPJWMXxCByFsEQI56ykh2BEqirnhKMxeJ69y7aX0boOOgO9Da_QSBWdD9A4D52XLbSd0WqHfNi4gGsXdRdtutgSYe21bBIDJcTZRksPlVs4H2GIfbM5BgdGtkGffO0T8HQze5zeZfOH2_vp9TxTtCQx0zVvMG1ylWtWFDXCTUWJqWjNjEyjoYIqlhZWFapqkmZEJm_ypqZY4xpxTifgYshde_fW6xDFygal21Z22vVBEMQQZ4xRltDzP-jS9b5Lv0tUUVDGeUkShQdKeReC10asvV1JvxEYia1-MegXSb_Y6hdl6jn7Su7rlW5-Or59J4AMQLJmuxftf5_-P_UTmGWPJw</recordid><startdate>20190201</startdate><enddate>20190201</enddate><creator>Färkkilä, Esa</creator><creator>Rautemaa-Richardson, Riina</creator><creator>Färkkilä, Anniina</creator><creator>Grönholm, Lotta</creator><creator>Lauhio, Anneli</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20190201</creationdate><title>Evaluation of risk factors for oral infection with potential for spread in a 1-year cohort study</title><author>Färkkilä, Esa ; Rautemaa-Richardson, Riina ; Färkkilä, Anniina ; Grönholm, Lotta ; Lauhio, Anneli</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-eb8d13d4c4e655b01d932f93b6fa518053c6c6c1c909b24360f4d4db31e1b0883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cancer</topic><topic>Cohort analysis</topic><topic>Cohort Studies</topic><topic>Demography</topic><topic>Dentistry</topic><topic>Drug addiction</topic><topic>Female</topic><topic>Finland</topic><topic>Humans</topic><topic>Immunosuppressive agents</topic><topic>Infections - complications</topic><topic>Infections - etiology</topic><topic>Male</topic><topic>Maxillofacial</topic><topic>Medicine</topic><topic>Middle Aged</topic><topic>Oral infection</topic><topic>Original Article</topic><topic>Patients</topic><topic>Risk Factors</topic><topic>Stomatognathic Diseases - complications</topic><topic>Stomatognathic Diseases - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Färkkilä, Esa</creatorcontrib><creatorcontrib>Rautemaa-Richardson, Riina</creatorcontrib><creatorcontrib>Färkkilä, Anniina</creatorcontrib><creatorcontrib>Grönholm, Lotta</creatorcontrib><creatorcontrib>Lauhio, Anneli</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical oral investigations</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Färkkilä, Esa</au><au>Rautemaa-Richardson, Riina</au><au>Färkkilä, Anniina</au><au>Grönholm, Lotta</au><au>Lauhio, Anneli</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of risk factors for oral infection with potential for spread in a 1-year cohort study</atitle><jtitle>Clinical oral investigations</jtitle><stitle>Clin Oral Invest</stitle><addtitle>Clin Oral Investig</addtitle><date>2019-02-01</date><risdate>2019</risdate><volume>23</volume><issue>2</issue><spage>905</spage><epage>911</epage><pages>905-911</pages><issn>1432-6981</issn><eissn>1436-3771</eissn><abstract>Objectives
To determine the frequency of oral infection with potential for spread (OIPS) and behavioural risk factors in patients referred to a regional tertiary care-centre for OIPS assessment and clearance.
Materials and methods
A database search of all referrals to the Oral and Maxillofacial Diseases unit of HUH in 2009 was performed. Of the 2807 referrals, 408 were due to a known or suspected OIPS. The electronic patient records of these patients were analysed for patient demographics, lifestyle factors, radiological findings and clinical oral findings. Risk factors for OIPS were analysed using logistic regression and using the significant factors in univariate analyses in the multivariate models.
Results
The mean age of the patients was 58 years. Most patients (
n
= 270, 66%) were referred due to upcoming cancer or other immunosuppressive therapy. The majority (
n
= 314, 77%) were diagnosed with one or more OIPS. In univariate analyses, smoking (OR 3.2, 95% CI 1.6–6.4;
p
= 0.0006), male gender (OR 1.7, 95% CI 1.1–2.8;
p
= 0.02), excessive alcohol use (OR 3.0, 95% 1.1–7.9;
p
= 0.03) and irregular dental care (OR 4.8, 95% CI 2.6–8.8;
p
< 0.0001) were risk factors for OIPS. However, in multivariate analyses, smoking was the only independent risk factor for OIPS (OR 3.6, 95% CI 1.2–11.8;
p
= 0.02).
Conclusions
OIPS are common in patients referred for OIPS clearance, and smoking was identified as an independent behavioural risk factor for them. These findings highlight the burden of disease in this patient group and the importance of smoking cessation encouragement.
Clinical relevance
To identify patients at increased risk of OIPS.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29948280</pmid><doi>10.1007/s00784-018-2518-7</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1432-6981 |
| ispartof | Clinical oral investigations, 2019-02, Vol.23 (2), p.905-911 |
| issn | 1432-6981 1436-3771 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2060866636 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Aged Aged, 80 and over Cancer Cohort analysis Cohort Studies Demography Dentistry Drug addiction Female Finland Humans Immunosuppressive agents Infections - complications Infections - etiology Male Maxillofacial Medicine Middle Aged Oral infection Original Article Patients Risk Factors Stomatognathic Diseases - complications Stomatognathic Diseases - etiology |
| title | Evaluation of risk factors for oral infection with potential for spread in a 1-year cohort study |
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