HDAC6 at Crossroads of Infection and Innate Immunity

Histone deacetylase 6 (HDAC6) acts by enzyme-dependent and -independent mechanisms to regulate diverse cellular processes including autophagy, the ubiquitin proteasome system, and cell migration. HDAC6 also has emerging roles in innate immunity, including pathogen sensing and destruction, thus placi...

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Veröffentlicht in:	Trends in immunology 2018-08, Vol.39 (8), p.591-595
Hauptverfasser:	Moreno-Gonzalo, Olga, Mayor, Federico, Sánchez-Madrid, Francisco
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy bacterial and viral infection Bacterial infections Cell migration Cytokines deacetylase HDAC6 Histone deacetylase Infections inflammation Innate immunity Kinases Nitric oxide Phagocytosis Proteasomes Proteins Rodents Sepsis Ubiquitin Viral infections Viruses
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