Zoledronic acid is superior to tenofovir disoproxil fumarate-switching for low bone mineral density in adults with HIV

Zoledronic acid is superior to tenofovir disoproxil fumarate-switching for low bone mineral density in adults with HIV

To compare the effects of switching tenofovir disoproxil fumarate (TDF) or treatment with an intravenous bisphosphonate on bone mineral density (BMD) in HIV-positive adults with low bone mass. Two-year, randomized, open-label study at 10 sites in Australia and Spain. Of 112 adults on TDF-based antir...

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Veröffentlicht in:AIDS (London) 2018-09, Vol.32 (14), p.1967-1975
Hauptverfasser: Hoy, Jennifer F, Richardson, Robyn, Ebeling, Peter R, Rojas, Jhon, Pocock, Nicholas, Kerr, Stephen J, Martinez, Esteban, Carr, Andrew
Format: Artikel
Sprache:eng
Schlagworte:
AIDS/HIV
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Zusammenfassung:To compare the effects of switching tenofovir disoproxil fumarate (TDF) or treatment with an intravenous bisphosphonate on bone mineral density (BMD) in HIV-positive adults with low bone mass. Two-year, randomized, open-label study at 10 sites in Australia and Spain. Of 112 adults on TDF-based antiretroviral therapy (ART) screened, 87 with low BMD (T-score 
ISSN:0269-9370
1473-5571
DOI:10.1097/QAD.0000000000001911