Intrathecal administration of antioxidants attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat
Research highlights ► Mechanical pain hypersensitivity was increased in the sleep-deprived rat. ► Intrathecally administered antioxidants reduced hypersensitivity in sleep-deprived animals. ► Spinal oxidative stress contributes to pain hypersensitivity induced by sleep deprivation.
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| Veröffentlicht in: | Scandinavian journal of pain 2011-04, Vol.2 (2), p.64-69 |
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| container_end_page | 69 |
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| container_issue | 2 |
| container_start_page | 64 |
| container_title | Scandinavian journal of pain |
| container_volume | 2 |
| creator | Wei, Hong Huang, Jin-Lu Hao, Bin Wang, Yan-Chao Nian, Gong Ma, Ai-Niu Li, Xin-Yan Wang, Yong-Xiang Pertovaara, Antti |
| description | Research highlights ► Mechanical pain hypersensitivity was increased in the sleep-deprived rat. ► Intrathecally administered antioxidants reduced hypersensitivity in sleep-deprived animals. ► Spinal oxidative stress contributes to pain hypersensitivity induced by sleep deprivation. |
| doi_str_mv | 10.1016/j.sjpain.2011.01.001 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1877-8860 |
| ispartof | Scandinavian journal of pain, 2011-04, Vol.2 (2), p.64-69 |
| issn | 1877-8860 1877-8879 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2057114179 |
| source | De Gruyter Open Access Journals |
| subjects | Antioxidant Internal Medicine Oxidative stress Pain hypersensitivity Pain Medicine REM sleep deprivation Spinal sensitization Tactile allodynia |
| title | Intrathecal administration of antioxidants attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat |
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