Outcomes of Magnetic Resonance Imaging–Ultrasound Fusion Prostate Biopsy of PI-RADS 3, 4, and 5 Lesions

Prostate cancer is the second most common cancer in men worldwide [1], and is the fifth leading cause of cancer death in men with 307,500 deaths in 2012 [1]. Approximately two-thirds of prostate cancer cases are disproportionately diagnosed in the developed world, largely due to prostate cancer screening practices [1]. However, some detected cancers are so low grade and slow growing that they are unlikely to affect the individual in his lifetime [2]. Treatment with radical prostatectomy, brachytherapy, or external bean radiotherapy carries risks including erectile dysfunction and urinary incontinence [2].