Relationship Between Degree of Coronary Vascular Bed Involvement and Characteristics of Stenting With Short-Term and Long-Term Outcomes in Patients With Acute Coronary Syndrome (Data of the RECORD-3 Registry)

It was shown in this retrospective analysis of data from the Russian registry of acute coronary syndromes (ACS) RECORD-3 that compared with patients in whom coronary angiography revealed no hemodynamically significant (>50 %) stenosis, patients with such stenosis in one vessel (with single vessel disease - SVD) and especially in multiple vessels (with multi-vessel disease - MVD) had much more anamnestic and clinical factors of unfavorable prognosis. Rates of all cause death as well as composite of death and new myocardial infarction (MI) during hospitalization in patients without significant stenosis and those with SVD were not significantly different but rates of these outcomes among patients with MVD were significantly higher than among patients with SVD or without significant stenosis. Presence of MVD was associated with worse remote outcomes developed after discharge from hospital compared with absence of significant stenosis (rate of death, MI, and urgent revascularization was significantly higher for 6 and 12 months after ACS), and compared with SVD (rate of death, MI, and urgent revascularization was significantly higher for 12 months after ACS). During percutaneous coronary interventions bare metal stents were used 2 times more often than drug eluting stents. Implantation of 2 or more stents compared with implantation of 1 stent was associated with higher rate of unfavorable outcomes (composite of death, MI, and urgent revascularization) developed after hospital discharge during 12 months after onset of ACS.