Characterization of group B Streptococcus isolated from sterile and non-sterile specimens in China

Group B streptococcus (GBS) is a leading cause of invasive neonatal infections and has increasingly been associated with invasive diseases in non-pregnant adults. We collected 113 GBS isolates recovered from sterile and non-sterile specimens from seven tertiary hospitals in China between October 201...

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Veröffentlicht in:	Diagnostic microbiology and infectious disease 2018-09, Vol.92 (1), p.56-61
Hauptverfasser:	Nie, Shuping, Lu, Xuedong, Jin, Zhengjiang, Gao, Juyi, Ma, Dongli, Deng, Jikui, Wu, Xianglin, Hu, Yan-Wei, Zheng, Lei, Wang, Qian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents - therapeutic use Child Child, Preschool China Clonal complex Drug Resistance, Bacterial - drug effects Drug Resistance, Bacterial - genetics Female Genotype Group B Streptococcus Humans Infant Infant, Newborn Male Microbial Sensitivity Tests - methods Middle Aged Multilocus sequence typing Multilocus Sequence Typing - methods Retrospective Studies Serogroup Serotyping Serotyping - methods Streptococcal Infections - drug therapy Streptococcal Infections - microbiology Streptococcus - drug effects Streptococcus - genetics Streptococcus - isolation & purification Virulence factor Young Adult
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Zusammenfassung:	Group B streptococcus (GBS) is a leading cause of invasive neonatal infections and has increasingly been associated with invasive diseases in non-pregnant adults. We collected 113 GBS isolates recovered from sterile and non-sterile specimens from seven tertiary hospitals in China between October 2014 and September 2016. Medical records were retrospectively reviewed and the sequence types, serotypes, virulence, and antimicrobial resistance profiles of the isolates were characterized and correlated. Significantly higher C-reactive protein and procalcitonin levels and absolute neutrophil counts were observed in patients with invasive infections than in those with non-invasive infections (P
ISSN:	0732-8893 1879-0070
DOI:	10.1016/j.diagmicrobio.2018.04.014