Supraciliary versus intrascleral implantation with hema implant (Esnoper V‐2000) in deep sclerectomy: a multicenter randomized controlled trial

Purpose To compare the supraciliary versus intrascleral implantation of the hema implant (Esnoper V‐2000) in terms of the efficacy and safety in nonpenetrating deep sclerectomy (NPDS). Patients and methods Prospective, randomized, unmasked, competitive and multicenter clinical trial. Eighty‐three eyes from 83 patients suffering from open‐angle glaucoma (40 males, 43 females) were enrolled and followed up for 12 months. Main outcome measures were best‐corrected visual acuity (BCVA), intraocular pressure (IOP), perimetry (mean defect, MD and Visual Field Index, VFI), pachymetry, number of antiglaucoma medications and analysis of blebs according Moorfields Bleb Grading. Results The IOP was significantly reduced in both groups from 23.74 ± 6.9 mmHg (implant sutured to the sclera, group 1) and 23.46 ± 6.47 mmHg (implant placed in the suprachoroidal space, group 2) to 15.43 ± 4.27 mmHg (p