Increased Cardiovascular Risk in Hypertriglyceridemic Patients With Statin-Controlled LDL Cholesterol

Abstract Context Real-world evidence of the relationship between high triglyceride (TG) levels and cardiovascular (CV) disease (CVD) risk among statin-treated patients with low-density lipoprotein cholesterol (LDL-C) control is lacking. Objective We aimed to compare CVD and mortality risk between pa...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2018-08, Vol.103 (8), p.3019-3027
Hauptverfasser:	Nichols, Gregory A, Philip, Sephy, Reynolds, Kristi, Granowitz, Craig B, Fazio, Sergio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Angina Arteriosclerosis Cardiovascular diseases Cardiovascular Diseases - epidemiology Cardiovascular Diseases - etiology Cardiovascular Diseases - mortality Cerebral infarction Cholesterol Cholesterol, LDL - blood Cohort Studies Female Health risk assessment Health risks Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hypertriglyceridemia - blood Hypertriglyceridemia - complications Hypertriglyceridemia - drug therapy Hypertriglyceridemia - epidemiology Incidence Longitudinal Studies Low density lipoprotein Male Middle Aged Mortality Myocardial infarction Risk Factors Risk groups Statins Stroke
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Zusammenfassung:	Abstract Context Real-world evidence of the relationship between high triglyceride (TG) levels and cardiovascular (CV) disease (CVD) risk among statin-treated patients with low-density lipoprotein cholesterol (LDL-C) control is lacking. Objective We aimed to compare CVD and mortality risk between patients with high vs normal TGs. Design Longitudinal observational cohort study. Setting Integrated delivery system. Patients Patients aged ≥45 years whose TG level was either
ISSN:	0021-972X 1945-7197
DOI:	10.1210/jc.2018-00470