Effect of Vitamin C Supplementation on Oxidative Stress Markers Following Thirty Minutes Moderate Intensity Exercise in Healthy Young Women

The aim of this double blind randomized controlled trial was to determine the effect of Vitamin C supplementation on oxidative stress following 30 min moderate intensity exercise. Forty-nine healthy young women randomly assigned into 500 mg day super(-1) vitamin C supplement (n = 25) or placebo (n = 24) groups for two weeks. Before supplementation and on the day after the intervention period, fasting blood samples were taken. Then all participants ran (1.4-1.7 m sec super(-1)) for 30 min. Third blood samples were taken at the end of exercise. Plasma malondialdehyde (MDA) and vitamin C were measured using HPLC method. Plasma total glutathione was measured with ELISA method. No significant differences were observed in demographic and vitamin C intakes before intervention between groups. Plasma MDA levels decreased and plasma total glutathione increased significantly (p