Preparation of four 1,4‐dihydropyridine derivatives (DHPs) labeled with carbon‐14

The importance of DHPs compounds and the need for examining the mechanism of their effect, mandated us to synthesize a number of carbon‐14 labeled 1,4‐dihydropyridine derivatives for pharmacological studies. Simple preparation and suitable radiochemical yield were advantages of this preparation. In...

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Veröffentlicht in:Journal of labelled compounds & radiopharmaceuticals 2018-08, Vol.61 (10), p.796-798
Hauptverfasser: Faghih, Mohammad Amin Ahmadi, Moslemin, Mohammad Hossein, Shirvani, Gholamhossein, Javaheri, Mohsen
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container_end_page 798
container_issue 10
container_start_page 796
container_title Journal of labelled compounds & radiopharmaceuticals
container_volume 61
creator Faghih, Mohammad Amin Ahmadi
Moslemin, Mohammad Hossein
Shirvani, Gholamhossein
Javaheri, Mohsen
description The importance of DHPs compounds and the need for examining the mechanism of their effect, mandated us to synthesize a number of carbon‐14 labeled 1,4‐dihydropyridine derivatives for pharmacological studies. Simple preparation and suitable radiochemical yield were advantages of this preparation. In this paper, 1,4‐dihydropyridine derivatives (DHPs) synthesis was developed, from 2 perspectives: the structural diversity of synthesis and the increasing number of labeled sites.
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subjects Antitubercular
Carbon
Carbon‐14
Derivatives
Dihydropyridine
Dihydropyridine (DHP)
labeling
Pharmacology
Radiochemistry
title Preparation of four 1,4‐dihydropyridine derivatives (DHPs) labeled with carbon‐14
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