Preparation of four 1,4‐dihydropyridine derivatives (DHPs) labeled with carbon‐14
The importance of DHPs compounds and the need for examining the mechanism of their effect, mandated us to synthesize a number of carbon‐14 labeled 1,4‐dihydropyridine derivatives for pharmacological studies. Simple preparation and suitable radiochemical yield were advantages of this preparation. In...
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Veröffentlicht in: | Journal of labelled compounds & radiopharmaceuticals 2018-08, Vol.61 (10), p.796-798 |
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container_title | Journal of labelled compounds & radiopharmaceuticals |
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creator | Faghih, Mohammad Amin Ahmadi Moslemin, Mohammad Hossein Shirvani, Gholamhossein Javaheri, Mohsen |
description | The importance of DHPs compounds and the need for examining the mechanism of their effect, mandated us to synthesize a number of carbon‐14 labeled 1,4‐dihydropyridine derivatives for pharmacological studies. Simple preparation and suitable radiochemical yield were advantages of this preparation.
In this paper, 1,4‐dihydropyridine derivatives (DHPs) synthesis was developed, from 2 perspectives: the structural diversity of synthesis and the increasing number of labeled sites. |
doi_str_mv | 10.1002/jlcr.3642 |
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In this paper, 1,4‐dihydropyridine derivatives (DHPs) synthesis was developed, from 2 perspectives: the structural diversity of synthesis and the increasing number of labeled sites.</description><subject>Antitubercular</subject><subject>Carbon</subject><subject>Carbon‐14</subject><subject>Derivatives</subject><subject>Dihydropyridine</subject><subject>Dihydropyridine (DHP)</subject><subject>labeling</subject><subject>Pharmacology</subject><subject>Radiochemistry</subject><issn>0362-4803</issn><issn>1099-1344</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp10M9KAzEQBvAgitbqwReQBS8Kbk0y2ezmKPU_BUX0vGSTWUzZ7takVXrzEXxGn8TUqgfBUw7zm4_JR8geowNGKT8ZN8YPQAq-RnqMKpUyEGKd9ChInoqCwhbZDmFMaZwJsUm2uMoVU1L1yOOdx6n2eua6NunqpO7mPmHH4uPt3bqnhfXddOGddS0mFr17ifAFQ3J4dnUXjpJGV9igTV7d7Ckx2lddGxeZ2CEbtW4C7n6_ffJ4cf4wvEpHt5fXw9NRaiADniLazEioKyuVYDkYAJ5bKABNJXIrTW4ZVFzWmPGskJnihVTIdSVFoUBr6JPDVe7Ud89zDLNy4oLBptEtdvNQciogZxkVKtKDP3Qcv9rG66Iqioggl1EdrZTxXQge63Lq3UT7Rclouey6XHZdLruOdv87cV5N0P7Kn3IjOFmBV9fg4v-k8mY0vP-K_AQmPojg</recordid><startdate>201808</startdate><enddate>201808</enddate><creator>Faghih, Mohammad Amin Ahmadi</creator><creator>Moslemin, Mohammad Hossein</creator><creator>Shirvani, Gholamhossein</creator><creator>Javaheri, Mohsen</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5827-2223</orcidid></search><sort><creationdate>201808</creationdate><title>Preparation of four 1,4‐dihydropyridine derivatives (DHPs) labeled with carbon‐14</title><author>Faghih, Mohammad Amin Ahmadi ; Moslemin, Mohammad Hossein ; Shirvani, Gholamhossein ; Javaheri, Mohsen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3532-eed5c63fbd694173c3327d383ecb47d6c7d13b26fe52586592869e2ab64893aa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Antitubercular</topic><topic>Carbon</topic><topic>Carbon‐14</topic><topic>Derivatives</topic><topic>Dihydropyridine</topic><topic>Dihydropyridine (DHP)</topic><topic>labeling</topic><topic>Pharmacology</topic><topic>Radiochemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Faghih, Mohammad Amin Ahmadi</creatorcontrib><creatorcontrib>Moslemin, Mohammad Hossein</creatorcontrib><creatorcontrib>Shirvani, Gholamhossein</creatorcontrib><creatorcontrib>Javaheri, Mohsen</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of labelled compounds & radiopharmaceuticals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Faghih, Mohammad Amin Ahmadi</au><au>Moslemin, Mohammad Hossein</au><au>Shirvani, Gholamhossein</au><au>Javaheri, Mohsen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preparation of four 1,4‐dihydropyridine derivatives (DHPs) labeled with carbon‐14</atitle><jtitle>Journal of labelled compounds & radiopharmaceuticals</jtitle><addtitle>J Labelled Comp Radiopharm</addtitle><date>2018-08</date><risdate>2018</risdate><volume>61</volume><issue>10</issue><spage>796</spage><epage>798</epage><pages>796-798</pages><issn>0362-4803</issn><eissn>1099-1344</eissn><abstract>The importance of DHPs compounds and the need for examining the mechanism of their effect, mandated us to synthesize a number of carbon‐14 labeled 1,4‐dihydropyridine derivatives for pharmacological studies. Simple preparation and suitable radiochemical yield were advantages of this preparation.
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subjects | Antitubercular Carbon Carbon‐14 Derivatives Dihydropyridine Dihydropyridine (DHP) labeling Pharmacology Radiochemistry |
title | Preparation of four 1,4‐dihydropyridine derivatives (DHPs) labeled with carbon‐14 |
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