Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma

We report the case of a patient with acute lymphoblastic leukaemia who, after the initiation of treatment with vincristine (VCR), developed a fulminant motor polyradiculoneuropathy resembling an axonal variant of Guillain‐Barré syndrome (GBS). This report shows that differentiating between axonal GB...

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Veröffentlicht in:European journal of neurology 2007-07, Vol.14 (7), p.826-828
Hauptverfasser: González Pérez, P., Serrano-Pozo, A., Franco-Macías, E., Montes-Latorre, E., Gómez-Aranda, F., Campos, T.
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Sprache:eng
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Zusammenfassung:We report the case of a patient with acute lymphoblastic leukaemia who, after the initiation of treatment with vincristine (VCR), developed a fulminant motor polyradiculoneuropathy resembling an axonal variant of Guillain‐Barré syndrome (GBS). This report shows that differentiating between axonal GBS and VCR‐induced acute neurotoxicity may be a challenge for clinicians.
ISSN:1351-5101
1468-1331
1471-0552
DOI:10.1111/j.1468-1331.2007.01842.x