Multi‐omics in high‐grade serous ovarian cancer: Biomarkers from genome to the immunome

Multi‐omics in high‐grade serous ovarian cancer: Biomarkers from genome to the immunome

Epithelial ovarian cancer (EOC) is a lethal gynaecological disease that imposes significant burden on health care and patient quality of life. High‐grade serous carcinoma of the ovary (HGSC) is the most prevalent histological type of EOC. A vast majority of HGSC cases are diagnosed at late stages of...

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Veröffentlicht in:American journal of reproductive immunology (1989) 2018-08, Vol.80 (2), p.e12975-n/a
Hauptverfasser: Clifford, Cole, Vitkin, Natasha, Nersesian, Sarah, Reid‐Schachter, Gillian, Francis, Julie‐Ann, Koti, Madhuri
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Clinical trials
Genomes
genomics
Immune system
immunomics
Immunotherapy
Ovarian cancer
Patients
Quality of life
Survival
Tumors
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Zusammenfassung:Epithelial ovarian cancer (EOC) is a lethal gynaecological disease that imposes significant burden on health care and patient quality of life. High‐grade serous carcinoma of the ovary (HGSC) is the most prevalent histological type of EOC. A vast majority of HGSC cases are diagnosed at late stages of the disease, limiting the opportunity for clinical intervention and resulting in a 10‐year survival rate of
ISSN:1046-7408
1600-0897
DOI:10.1111/aji.12975