Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis

INTRODUCTIONMerkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. CASE REPORTWe report a case of Merkel's abdominal carcinomas treated with extensive inguinal lymph...

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Veröffentlicht in:Journal of surgical case reports 2018, Vol.2018 (5), p.rjy098-rjy098
Hauptverfasser: Coppola Bottazzi, Enrico, Noviello, Adele, Moles, Nicola, Miro, Antonio, Striano, Augusto, Baiamonte, Mario, Esposito, Francesco, Crafa, Francesco
Format: Report
Sprache:eng
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Zusammenfassung:INTRODUCTIONMerkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. CASE REPORTWe report a case of Merkel's abdominal carcinomas treated with extensive inguinal lymphadenectomy and reconstruction of the abdominal wall and inguinal canal using prosthesis GORE® BIO-A®. DISCUSSIONImmunohistochemical analysis by tumor-specific markers is crucial for diagnosis and permits differentiation from other tumors of the skin. MCC is an aggressive tumor with poor prognosis. CONCLUSIONSFor primary tumors without indications of the presence of organ metastases complete surgical excision is the gold standard. Gore BIO-A is a biosynthetic prosthesis with manageable structure that allows it to be positioned and shaped according to needs, its strength provides for excellent support for the reconstruction of the inguinal canal wall.
ISSN:2042-8812
2042-8812
DOI:10.1093/jscr/rjy098