Bixin and lycopene modulation of free radical generation induced by cisplatin–DNA interaction

This work evaluated the modulation of reactive oxygen species (ROS) produced by the cisplatin–human DNA interaction in a cell-free experimental model by the carotenoids bixin and lycopene, extracted from natural dietary sources and purified through luminol- and Cypridina luciferin methoxy-analogue (...

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Veröffentlicht in:	Food chemistry 2009-04, Vol.113 (4), p.1113-1118
Hauptverfasser:	Rios, Alessandro de O., Antunes, Lusânia M.G., Bianchi, Maria de L.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	adverse effects bixin Carotenoids Chemiluminescence Cisplatin cisplatin-DNA interaction Cypridina DNA drug therapy free radicals humans in vitro studies lycopene microencapsulation oxidative stress Reactive oxygen species
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