Variation of Carotid Intima Media Thickness With Body Mass Index in Healthy Adults of Black African Descent
Objectives Studies have shown that common carotid intima media thickness (CIMT) measured by B‐mode sonography increases with body mass index (BMI) among subjects with cardiovascular diseases in different populations. However, association of body fat and subclinical atherosclerosis in the absence of...
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Veröffentlicht in: | Journal of ultrasound in medicine 2019-01, Vol.38 (1), p.123-130 |
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Sprache: | eng |
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Zusammenfassung: | Objectives
Studies have shown that common carotid intima media thickness (CIMT) measured by B‐mode sonography increases with body mass index (BMI) among subjects with cardiovascular diseases in different populations. However, association of body fat and subclinical atherosclerosis in the absence of these cardiovascular diseases is understudied. We aimed to evaluate the correlation between BMI and CIMT in a healthy adult population of black African ancestry.
Methods
This is a cross‐sectional prospective study in 300 consecutive apparently healthy subjects aged 18 to 70 years without history of hypertension, dyslipidemia, diabetes mellitus, and renal disease. Subjects' common carotid artery intima media thickness was measured with a 7.5‐MHz linear ultrasound transducer at a point 10 mm proximal to the carotid bulb. All subjects' biodata, medical history, anthropometric (weight and height from which BMI was calculated), laboratory (fasting lipid profile and blood glucose), and CIMT values were recorded on a pro forma. Data were analysed using SPSS version 21, and significant P was set at less than .05.
Results
The right, left, and average CIMT of both sides in our study subjects are 0.52 ± 0.11 mm, 0.51 ± 0.11 mm and 0.52 ± 0.11 mm respectively, with no significant difference between the right and left sides (P > .05). The right, left, and average CIMT increased with increasing age and BMI category (all P .05). Age (r = .824, .825, and .827; P |
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ISSN: | 0278-4297 1550-9613 |
DOI: | 10.1002/jum.14673 |